TRT Dosage Guidelines for Men

Testosterone Replacement Therapy (TRT) dosing must be carefully individualized to ensure both safety and effectiveness. Your provider determines the appropriate starting dose by evaluating comprehensive bloodwork, medical history, age, and symptoms. This personalized approach helps restore testosterone to a healthy range while minimizing unwanted side effects. AUA ¹

Many men receive TRT through intramuscular or subcutaneous injections, which offer precise control over dosing. However, your provider may also recommend alternative delivery systems—such as gels, patches, or pellets—if they better suit your lifestyle or medical needs. Each method requires establishing the optimal dose and dosing frequency to maintain stable testosterone levels throughout the treatment cycle. Endocrine Society Clinical Practice Guideline³

Ongoing monitoring is essential to successful TRT. Routine bloodwork allows your provider to measure testosterone, estradiol, hematocrit, and other key markers that influence both effectiveness and safety. Regular follow-up appointments enable precise dosage adjustments and help address any emerging symptoms or side effects. This data-driven approach ensures your therapy remains balanced, therapeutic, and aligned with long-term wellness goals. AAFP Recommendations²

Important Disclaimer

The information provided here is for educational purposes only and should not be considered medical advice. Testosterone Replacement Therapy (TRT) dosage and treatment must be personalized and supervised by a licensed healthcare professional.

Do not begin, change, or discontinue any hormone therapy without consulting your provider. For medical guidance specific to your health and hormone needs, please schedule an evaluation with a qualified practitioner.

1. American Urological Association (AUA) — Evaluation and Management of Testosterone Deficiency: AUA Guideline
2. American Academy of Family Physicians (AAFP) — Testosterone Replacement Therapy for Male Hypogonadism
3. Endocrine Society — Testosterone Therapy in Men with Hypogonadism: A Clinical Practice Guideline