Available in Capsules, Cream and Tablets
As we age, we become more susceptible to inflammation, decreased energy, and can even lose some of our natural ability to fight off disease. This can leave us feeling fatigued, more vulnerable to illness, and less able to keep up with the demands of daily life.
Metformin can assist you in leading a healthier, more fulfilling lifestyle by working at a cellular and molecular level to slow the aging process and improve metabolic function, energy levels, and overall vitality.
What is Metformin?
Metformin is a widely used prescription medication best known for managing type 2 diabetes, but its benefits go far beyond blood sugar control. In recent years, researchers have uncovered its potential as a powerful tool in the fight against aging.
Metformin works at the cellular level to improve insulin sensitivity, reduce inflammation, and enhance mitochondrial function—key factors that contribute to healthier aging.
Studies suggest that Metformin may help slow the aging process by influencing metabolic and genetic pathways associated with longevity. By promoting better cellular health and reducing oxidative stress, it supports the body's natural ability to repair itself and maintain vitality over time.
For individuals looking to take proactive steps toward a longer, healthier life, Metformin offers a promising and science-backed option.
Ordering is Easy and Convenient
Serving Pennsylvania, Florida, Virginia and Connecticut
Complete Our Online Intake Form
Fill out our short online intake form. Our doctor will review your information and determine if you're a good candidate for metformin.
Meet with Our Doctor
Meet with our doctor to discuss the benefits of metformin, how it works, potential side effects, and what to expect during treatment.
Receive Your Peptide at Home
Your metformin will be conveniently delivered to your home. You’ll receive detailed instructions on how to use it safely and effectively, along with ongoing support from our team to help you achieve the best results.
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The Sanctuary Wellness Institute is proud to work with medical wellness physicians who are experts in their field. Combining their expertise with a compassionate, informative and helpful approach to patient care allows us to provide an exceptional teleWellness patient experience.
Among our expert physician staff we have medical marijuana specialists, medical weight loss experts, a book author and an international speaker.
Dr. Desiree Granados, MD
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Dr. Megan Horsham, MD
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Dr. Kalpana Sundar, DO
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Very friendly, professional and helpful. Explained the process in detail and gave excellent advice.
Jim K.
Very wonderful people. Compassionate and understanding. Quick and efficient. I have used their services for multiple years and will continue.
Jason S.
Staff is always polite I’ve been using Sanctuary wellness for about 5 yrs have always had amazing experiences and being able to make apps for same day is a huge plus!!!️
Kristofer K.
Potential Benefits of Metformin
Recent research highlights Metformin's range of potential health benefits that extend well beyond its traditional use in managing type 2 diabetes, including:
- Enhanced Metabolic Function: Supports the body’s ability to efficiently manage energy, stabilize blood sugar, and maintain healthy blood pressure and cholesterol levels.
- Optimized Cellular Performance: Promotes the efficient functioning of cells, aiding in energy production, repair, growth, and communication throughout the body.
- Anti-Aging Effects: Metformin works by reducing chronic inflammation, enhancing mitochondrial function, and lowering oxidative stress—all of which are key contributors to cellular aging. It may also activate AMPK, a metabolic “master switch” that helps regulate energy use and promote cellular repair, potentially slowing the aging process and reducing age-related decline.
- Improved Insulin Sensitivity: Helps the body respond more effectively to insulin, making it easier to control blood sugar levels.
- Lower Blood Glucose Levels: Aids in reducing and stabilizing blood sugar, especially important for those with insulin resistance or type 2 diabetes.
- Reduced Cardiovascular Risk: Lowers the likelihood of heart disease by improving blood sugar control, lipid levels, and vascular function.
- Support for Weight Loss Management: Can assist with weight loss or maintenance by improving insulin sensitivity and reducing appetite in some individuals..
- Healthier Lipid Profile: Helps decrease levels of bad cholesterol (LDL) and triglycerides while potentially increasing good cholesterol (HDL).
Available Metformin Treatments
Capsules
Metformin capsules offer a controlled release of the medication, which can help reduce gastrointestinal side effects. This form is often ideal for individuals who are starting treatment or prefer a once-daily dose.
Cream
Our topical Metformin cream provides a unique option for those who prefer to avoid oral medications. It delivers the active ingredient directly through the skin, making it a suitable choice for localized benefits or individuals with digestive sensitivities.
Tablets
Metformin tablets are the most common form and are available in both immediate and extended-release formulations. They provide reliable blood sugar control and are a trusted option for long-term management.
Our providers will work with you to determine which formulation best aligns with your health needs, preferences, and any existing conditions.
Metformin Clinical Trials
Ongoing clinical trials are revealing metformin’s potential far beyond blood sugar control. The TAME Trial (Targeting Aging with Metformin) is exploring whether metformin can delay or prevent age-related diseases like heart disease, cancer, and dementia.
NIH-funded research, including the RECOVER initiative, is also investigating metformin’s role in reducing the risk and severity of long COVID, with some studies suggesting that people with diabetes taking metformin may be less likely to develop the condition.
In cancer research, the National Cancer Institute is funding studies on metformin’s ability to prevent lung cancer in high-risk individuals, along with its effects on other cancers. Additionally, trials are underway to determine whether metformin can help prevent Alzheimer’s disease or slow cognitive decline.
Metformin's preventive benefits were first highlighted in the Diabetes Prevention Program (DPP), a major NIH study that showed its effectiveness in reducing the risk of type 2 diabetes. Together, these studies point to metformin’s growing promise as a tool for promoting long-term health and longevity.
Metformin for Weight Loss
While metformin is primarily prescribed to manage blood sugar in individuals with type 2 diabetes or insulin resistance, it has also shown promise as a weight loss aid—especially for those with underlying metabolic issues. Metformin may support weight loss by improving insulin sensitivity, reducing appetite, and lowering glucose production in the liver.
Unlike many weight loss medications, metformin is not a stimulant and typically does not cause weight gain, making it a well-tolerated option for long-term use.
Though not FDA-approved specifically for weight loss, many healthcare providers use metformin off-label to help patients with obesity, PCOS, or prediabetes manage their weight more effectively. Results can vary, but when combined with healthy lifestyle changes, metformin may support gradual and sustainable weight loss.
Metformin Cost
At Sanctuary Wellness Institute, we offer metformin treatment at a straightforward and affordable price of $199 per month. This all-inclusive cost covers your prescribed metformin in the form that best suits your needs—capsules, cream, or tablets—as well as ongoing support from our experienced medical team.
There are no hidden fees or surprise charges, making it easy to plan your treatment and stay on track with your health goals. Whether you’re using metformin for metabolic support, weight management, or healthy aging, we’re here to help you get the most from your investment in wellness.
Metformin Potential Side Effects
While Metformin is generally well-tolerated and has a long track record of safe use, like any medication, it can cause side effects in some individuals. Most side effects are mild and tend to improve over time as your body adjusts to the medication.
The most common side effects include:
- Nausea and vomiting
- Diarrhea
- Stomach cramps or abdominal discomfort
- Gas and bloating
- Loss of appetite
- A metallic taste in the mouth
These effects are often temporary and can be minimized by taking Metformin with food or starting with a low dose that’s gradually increased. In rare cases, Metformin may lead to more serious side effects, such as:
- Vitamin B12 deficiency with long-term use
- Lactic acidosis, a rare but serious condition, usually occurring only in individuals with significantly impaired kidney or liver function
To reduce risk, Metformin should be used under the guidance of a qualified healthcare provider, who will monitor your health and adjust dosing as needed.
For most people, the potential benefits of Metformin—especially its promising anti-aging and metabolic effects—far outweigh the risks, making it a compelling option for supporting long-term health and vitality.
Frequently Asked Questions
Metformin is typically taken with meals to reduce the risk of gastrointestinal side effects. For most people, this means taking it with breakfast and dinner. Extended-release versions are often taken once daily with the evening meal. Always follow your healthcare provider’s instructions regarding timing and dosage.
Metformin begins to lower blood glucose levels within a few days of starting treatment, but it may take 1 to 2 weeks to see noticeable effects. For full therapeutic benefits—especially in managing insulin resistance or PCOS—it may take several weeks or even a few months.
Metformin has a half-life of about 6 hours, meaning it takes that long for half the dose to be eliminated. However, it usually takes around 4 to 5 half-lives (roughly 24–30 hours) for it to be fully cleared from your system. In extended-release forms, the effects may last longer.
For individuals with Polycystic Ovary Syndrome (PCOS), Metformin helps by improving insulin sensitivity, which can lower insulin levels and reduce the production of androgens (male hormones). This can lead to more regular menstrual cycles, improved ovulation, reduced acne and hair growth, and may also support weight loss and fertility.
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