Sanctuary Wellness Institute
Close this search box.

Does Semaglutide Suppress Appetite Immediately?

Semaglutide Suppress Appetite
Table of Contents

In recent years, semaglutide has garnered significant attention in the realm of weight loss. The medication has demonstrated an ability to not only regulate blood sugar levels, but also curb hunger. But just how quickly does semaglutide work to suppress appetite? In this article, we’ll delve into what you can expect regarding its effect on appetite.

What Is Semaglutide and How Does it Work for Weight Loss?

Semaglutide belongs to a class of drugs known as GLP-1 receptor agonists, which mimic the action of the naturally occurring glucagon-like peptide-1 hormone. This hormone plays a crucial role in regulating blood sugar levels by stimulating insulin secretion.

Semaglutide facilitates weight loss by affecting appetite centers in the brain, leading to reduced hunger and increased satiety. It also slows gastric emptying, keeping food in the stomach for longer.

How Long Does it Take for Semaglutide to Suppress Hunger?

Semaglutide typically starts to suppress appetite within the first few weeks of treatment. Patients often report noticing a reduction in hunger within one to two weeks, with more significant appetite suppression occurring after five weeks of consistent use.

However, individual responses can vary based on factors such as your dosage, your adherence to your treatment regimen, and your metabolism.

Does Semaglutide Zero Appetite?

Semaglutide has a significant impact on appetite. Many users report a marked decrease in hunger. However, it’s important to note that while semaglutide can suppress appetite, it doesn’t completely stifle it. Patients still experience hunger, albeit a less intense and more manageable hunger.

Some patients also report losing the ability to derive pleasure from eating, though this effect is rare.

Lose Weight with Semaglutide

How Long Does it Take to Lose Weight with Semaglutide?

The timeline for weight loss with semaglutide can vary depending on your starting weight, dosage, diet, and exercise routine. You may experience minor weight loss during the first month of your treatment, but it generally takes several months to achieve significant weight loss.
In a 2022 study, patients lost about 6% of their starting body fat after three months of treatment, and about 11% after six months.

What Factors Influence How Fast Semaglutide Works?

The speed at which semaglutide works for weight loss can vary significantly from person to person. Several factors influence how quickly you may see results, including:

  • Dosage: Higher doses of semaglutide can lead to more rapid weight loss.
  • Diet and Physical Activity: A well-balanced diet and regular exercise can accelerate the effects of semaglutide.
  • Metabolism: Individual differences in metabolic rates can affect how quickly the body responds to semaglutide.
  • Adherence to Treatment: Consistently taking semaglutide as prescribed will ensure optimal results. Missing doses or not following your prescribed regimen can delay weight loss.
  • Starting Weight and Health Status: Those with a higher starting weight or underlying health conditions may experience different rates of weight loss.
  • Genetics: Genetic factors can play a role in how responsive your body is to weight loss medication.

How Soon Do You Feel the Side Effects of Semaglutide?

With semaglutide treatment, the onset of side effects can vary among individuals. That said, people generally begin to experience side effects within the first week of their treatment. Common symptoms include gastrointestinal issues such as nausea, vomiting, and diarrhea.

These side effects tend to be more pronounced during the initial stages of treatment as the body adjusts to the medication. For most patients, they subside within a few weeks.


In conclusion, semaglutide represents a promising solution for those seeking to lose weight. While the timeline for experiencing reduced appetite and noticeable weight loss can vary, many patients see significant results within their first few weeks of treatment. It’s important to remember that individual factors such as dosage, diet, exercise, and metabolism play crucial roles in how quickly and effectively semaglutide works.

If you’ve struggled to lose weight through conventional methods, The Sanctuary Wellness Institute can help. Participants in our online medical weight loss program get their semaglutide injections delivered for self-administration and attend virtual visits with licensed physicians to track their progress and receive guidance. Book an evaluation today to find out whether you’re eligible.

How we reviewed this article: