- John DiBella
- Published: May 28, 2025
Biohacking in 2025 is no longer a fringe concept—it’s gone mainstream. Defined as making strategic changes to improve physical and mental performance, biohacking is now a part of daily life for a growing number of Americans. From tools and habits to data-driven insights, people are taking control of their health in increasingly personalized ways.
To better understand this shift, we surveyed over 1,000 Americans about their approach to health optimization. Whether through supplements, sleep tracking, or prescription medications, individuals are exploring a wide range of strategies to support their well-being, boost longevity, and enhance daily performance.
Key Findings:
- 67% identify as biohackers
- 94% think it’s healthy to optimize their body’s performance
- Mood and mental health are the most popular biohacking topics
- 82% think biohacking is worth the financial investment
- 65% purchase supplements
- 75% are inspired to optimize their wellness by social media
Biohacking Popularity & Social Media Influence
In 2025, the majority of Americans (67%) identify as biohackers, and nearly all (94%) think it’s healthy to optimize their body’s performance. Yet when it comes to which biohacking methods are most popular, responses are scattered. Over a quarter (26%) prefer mood and mental health topics, 23% prefer weight loss topics, and roughly 1 in 10 prefer cognitive enhancements, anti-aging, and gut health.
One reason biohacking is becoming popular is the rise of readily-available information in multiple formats. The top source is social media (67%), followed by medical studies (49%), podcasts (44%), blogs (34%), and books (32%).
Americans Invest over $200 Monthly in Biohacking
In addition to time and habit changes, biohacking often comes with a financial investment—averaging $214 per month. Still, 82% of people say it’s worth the cost. Most are putting their money toward supplements (65%), followed by prescription medications (11%) and health apps (7%). Only 17% report not spending any money on biohacking at all.
Why do Americans biohack? The benefits most important to them include:
- Longevity – 20%
- Mental clarity/focus – 19%
- Physical appearance – 15%
- Energy and productivity – 13%
- Immunity boost – 13%
Social Media’s Influence on Biohacking
While social media can have its downfalls, health can be a positive benefit at times: 75% are inspired by social media to optimize their wellness.
However, men and women alike feel social media pressure. When it comes to appearance, 69% feel pressured to look a specific way – 64% of men and 74% of women. Additionally, 41% feel like they’re falling behind others when it comes to wellness, especially women (47% of women and 35% of men).
Popular Biohacking Methods
Biohacking is gaining widespread traction, with 64% of Americans trying a new method in 2025. The most popular biohacking strategies reflect a blend of traditional wellness and emerging trends. A majority (75%) take vitamins or supplements, while 50% practice meditation and 40% engage in fasting. Others are following specific diets such as keto (36%) or experimenting with grounding techniques (25%).
Popular Supplements
When it comes to supplements, essential vitamins and minerals lead the pack, taken by 70% of users. Sleep aids like melatonin and magnesium are also widely used (44%), followed by antioxidants and anti-inflammatories such as turmeric or CBD (37%). Cognitive enhancers like lion’s mane and cordyceps (30%) and anti-anxiety compounds like L-Theanine and GABA (15%) round out the list. Notably, more than one in three users report major improvements from taking these supplements.
The Rise of Prescriptions in Biohacking
Currently, 21% report taking weight loss prescriptions. More specifically, GLP-1 medications like Ozempic and Wegovy are the most commonly used wellness prescriptions (18%). Additional prescriptions people are taking for body optimization include metformin (13%), NAD+ (7%), and sermorelin (6%). The success rate: 18% say these treatments have led to major improvements.
Looking ahead, GLP-1s remain the most anticipated prescription to try in 2025 (16%), along with sermorelin (10%), NAD+ (9%), and metformin (8%).
Biohacking with Food and Drinks
Nutrition also plays a key role in biohacking efforts. Popular wellness foods and drinks include local honey (57%), electrolyte beverages (45%), prebiotic/probiotic sodas (36%), fermented foods (35%), and carrot salads (34%). Over one in four Americans say they’ve seen significant health improvements from incorporating these items into their diets.
How Americans Track Their Health
Americans are taking a proactive approach to wellness by closely monitoring their health data. Weight is the most commonly tracked metric (66%), followed by calories (53%), workouts (52%), mood and mental health (41%), water intake (40%), and key vitals (36%). This reflects a growing trend toward holistic health management, extending beyond fitness into mental and emotional well-being.
While tracking is popular, privacy remains a major concern. More than half of Americans (56%) worry about how their body data is used—an issue more common among women (60%) than men (52%).
Digital tools are at the center of most wellness tracking. Phone apps lead the way at 53%, followed by the Apple Watch (45%) and FitBit (25%). Perhaps due to cost, only 3% report using an Oura Ring.
When it comes to specific types of health apps, workout trackers are the most widely used (45%), followed by calorie trackers (40%), weight tracking tools (39%), and guided workout plans (37%). Sleep tracking (32%) and mindfulness or meditation apps (30%) are also gaining traction, indicating that Americans are looking to balance physical performance with rest and mental clarity.
Biohacking Promotes Customized Health Journeys
Despite the financial and emotional investments involved, most people feel that biohacking is worth it. Whether motivated by longevity, mental clarity, or improved appearance, individuals are customizing their health journeys in ways that align with their personal goals. As interest continues to grow, the future of wellness may look less like a one-size-fits-all model and more like a toolkit—empowering each person to build a better version of themselves.
Methodology:
In May 2025, we surveyed 1,002 people about their health habits and body optimization tactics. Ages ranged from 18 to 99, with an average age of 40. 49% were women, 50% were men, 1% were nonbinary, and less than 1% would rather not say.
Fair use:
When using this data and research, please attribute by linking to this study and citing https://sanctuarywellnessinstitute.com/.
How we reviewed this article:
Current Version
John DiBella is the co-founder and CEO at The Sanctuary Wellness Institute. His goal is to foster healthier lifestyles to improve individuals’ quality of life and health span through online medical and non-medical services. When he’s not writing blogs about medical marijuana, he enjoys hiking, camping, surfing and sailing.
