Viagra (Sildenafil) vs. Cialis (Tadalafil): Which Is Better?

Erectile dysfunction (ED) is a common condition that affects millions of men around the world. Fortunately, effective treatments are available. Two of the most well-known prescription medications for ED are Viagra (sildenafil) and Cialis (tadalafil). While both drugs improve blood flow to the penis and help men achieve and maintain an erection, they work differently in terms of onset time, duration, and potential side effects.

If you’re considering ED treatment, understanding the differences between sildenafil and tadalafil can help you make an informed decision with your healthcare provider.

About Sildenafil

Sildenafil is the active ingredient in Viagra, the first oral medication approved to treat ED. It belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. Sildenafil works by relaxing the blood vessels and increasing blood flow to the penis during sexual stimulation.

Viagra is typically taken as needed, about 30 to 60 minutes before sexual activity. Its effects usually last for about 4 to 6 hours. It’s most effective when taken on an empty stomach, as high-fat meals can delay its absorption.

About Tadalafil

Tadalafil, the active ingredient in Cialis, is also a PDE5 inhibitor used to treat ED. However, it has a much longer half-life than sildenafil, meaning it stays in the body longer and can provide extended benefits.

Cialis can be taken in two ways: as needed before sexual activity or once daily at a lower dose. When taken as needed, tadalafil takes about 30 to 45 minutes to start working, and its effects can last up to 36 hours. This extended window has earned it the nickname “the weekend pill.”

Sildenafil vs. Tadalafil: What’s the Difference?

Though both medications serve the same purpose, several key differences exist between sildenafil and tadalafil:

• Starts Working: Viagra and Cialis take about the same amount of time to start working, with Viagra usually taking 30-60 minutes to kick in and Cialis taking 30-45 minutes.
• Duration: Viagra is meant for short-term use, as its effects last for 4-6 hours. Cialis is sometimes referred to as “the weekend pill” because its effects can last for up to 36 hours.
• Flexibility for Use: Viagra is designed for on-the-spot use, while Cialis is adaptable for both scheduled and spontaneous moments.
• Affected by Food?: You should take Viagra on an empty stomach, as eating fatty foods with Viagra can delay its absorption. There are no known interactions of food and Cialis.
• Suitability: Viagra is best suited for short-term use and quick results, while Cialis is more effective for extended duration and greater spontaneity.