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Does Semaglutide Cause Fatigue?

Semaglutide Cause Fatigue
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In recent years, semaglutide has been hailed for its efficacy as a weight-loss medication. However, as with many drugs, it carries a number of potential side effects patients should be aware of, including fatigue. In this article, we’ll delve into the relationship between semaglutide and fatigue and provide tips for how to manage this side effect.

Does Semaglutide Make You Tired?

Fatigue is a common side effect of semaglutide. It’s essential to consult a healthcare provider if you experience persistent or severe tiredness while taking semaglutide.

Why Am I Tired on Semaglutide?

Semaglutide fatigue can be attributed to several factors. For one, the medication can alter metabolic processes and energy utilization, leading to feelings of exhaustion. Additionally, as semaglutide helps reduce food intake, the resulting caloric deficit can contribute to decreased energy levels.

Does Semaglutide Affect Sleep?

The effect of semaglutide on sleep can vary from patient to patient. Some individuals report trouble sleeping, while others don’t notice any change in their sleep patterns. Further research is needed to fully understand the influence of semaglutide on sleep.

How Long Does it Take Your Body to Adjust to Semaglutide?

You may experience side effects during the first few weeks of your semaglutide treatment as your body adapts to the medication. Most patients begin with a low dose that’s gradually increased to minimize these effects and allow the body to acclimate.

Increase Energy on Semaglutide

How to Increase Energy on Semaglutide?

If you’re seeking to combat semaglutide-induced fatigue, there are several strategies you can use, including:

  • Eat a Balanced Diet: Eating a diet rich in whole foods, including plenty of fruits, vegetables, lean proteins, and whole grains, can help sustain steady energy levels.
  • Hydrate: Adequate hydration is essential to maintaining your energy levels. Aim to drink plenty of water throughout the day.
  • Exercise: Incorporating regular physical activity, such as walking, jogging, or yoga, can help increase your energy levels.
  • Sleep: Ensuring you get seven to nine hours of quality sleep each night can significantly improve your energy and overall well-being.
  • Manage Stress: Engage in stress-reducing activities like meditation, deep breathing exercises, or hobbies you enjoy to prevent energy depletion.
  • Monitor Blood Sugar Levels: Keeping your blood sugar levels stable by eating small, frequent meals can help you avoid energy slumps.

What Are Other Side Effects of Semaglutide?

In addition to its fatigue, semaglutide carries several other side effects, including:

  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Abdominal pain
  • Fatigue
  • Dizziness
  • Headache

These side effects are fairly common and typically occur during the first few weeks of treatment. If they persist or become severe, it’s important to consult your doctor.

Some other less common but more severe side effects of semaglutide include:

  • Low blood sugar (hypoglycemia)
  • Kidney problems
  • Allergic reaction
  • Thyroid cancer
  • Gallbladder problems
  • Pancreatitis

If you experience any of these symptoms while taking semaglutide, seek immediate medical attention.


While semaglutide is an effective medication for weight loss, it’s important to be mindful of its side effects, including fatigue. Understanding how semaglutide affects your body and taking proactive steps to manage these side effects can help you maintain your energy levels and overall well-being while using the medication.

If you’re interested in losing weight with semaglutide, look no further than The Sanctuary Wellness Institute. When you enroll in our online medical weight loss program, you’ll receive your semaglutide injections at home for self-administration and meet regularly with a licensed physician to track your progress. Book an evaluation today to discover whether you’re eligible.

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