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Can You Drink Alcohol with Semaglutide?

Can You Drink Alcohol with Semaglutide?
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Semaglutide has emerged as a promising pharmaceutical option for those seeking to lose weight and/or manage type 2 diabetes. This medication, which is marketed under brand names like Ozempic, Rybelsus, and Wegovy, has helped many patients achieve their weight loss goals.

However, as with any medication, there are precautions that need to be taken when using semaglutide. In this blog, we’ll explore whether you should drink alcohol while on semaglutide and provide guidance so you can make safe and healthy decisions.

What Happens if You Drink Alcohol While Taking Semaglutide?

Combining alcohol with semaglutide can lead to severe side effects. For one, alcohol can exacerbate semaglutide’s gastric side effects, increasing your risk of nausea, vomiting, and stomach discomfort.

Additionally, consuming alcohol while on semaglutide can lead to fluctuations in blood sugar levels, which can pose significant health risks, particularly for individuals with diabetes. It’s also worth noting that alcohol contains calories that may compromise your weight loss efforts.

How Much Alcohol Can You Drink on Semaglutide?

For those taking semaglutide, medical professionals recommend limiting alcohol intake due to the increased risk of hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar) drinking poses. Generally, this means consuming no more than one drink per day for women and two for men.

While occasional, moderate drinking on semaglutide may not be prohibited, it’s still advisable to consult your healthcare provider to gain an understanding of your individual risk factors and determine an appropriate level of alcohol consumption for you.

What Alcoholic Drinks Should You Avoid While Taking Ozempic?

When taking Ozempic, certain alcoholic beverages should be avoided to prevent adverse reactions and ensure the medication’s efficacy. Such beverages include:

  • High-Carbohydrate Beers: Many beers, especially those that are craft or sweetened, contain high levels of carbohydrates that can induce fluctuations in blood sugar levels.
  • Sugary Mixed Drinks: Cocktails mixed with sodas, juices, syrups, and/or creams tend to be high in sugar and calories, meaning they can cause blood sugar spikes and weight gain.
  • Fortified Wines: Sweet varieties of wine, such as port or sherry, have higher sugar content that can be detrimental for individuals trying to manage their blood sugar levels.
  • Heavy Liquors: Consuming spirits in large quantities can lead to rapid changes in blood sugar levels and potentially cause them to drop to dangerously low levels.

Is it Harder to Get Drunk on Ozempic?

Many users have reported that the same amount of alcohol that used to get them drunk no longer affects them since starting Ozempic. While there isn’t yet sufficient research to confirm this effect, preliminary studies have indicated that semaglutide can dampen alcohol cravings.

Guidelines for Drinking Alcohol While Taking Ozempic

Consider the following guidelines before drinking on Ozempic:

  • Consult Your Healthcare Provider: Before consuming alcohol on Ozempic, seek guidance from your healthcare provider regarding how often and how much you can drink.
  • Limit Your Alcohol Intake: Be sure to limit your alcohol consumption, even if your doctor says you can drink on Ozempic. Moderate drinking generally means one drink per day for women and up to two drinks per day for men.
  • Monitor Your Blood Sugar Levels: Alcohol can interfere with blood sugar levels. People taking Ozempic should monitor their blood sugar more frequently when consuming alcohol to avoid hypoglycemia or hyperglycemia.
  • Consider The Content of Your Drinks: Since Ozempic is often prescribed for weight management, it’s critical to consider the caloric and carbohydrate content of your chosen alcoholic drinks.
  • Stay Hydrated: Alcohol can lead to dehydration, which is especially risky for individuals managing diabetes. Aim to drink a glass of water between each alcoholic beverage you consume.
  • Know the Signs of Low Blood Sugar: Since Ozempic can lower blood sugar and alcohol can compound this effect, it’s important to be aware of hypoglycemia symptoms like dizziness, confusion, sweating, and rapid heartbeat.


In conclusion, while it may not be necessary to completely abstain from alcohol while taking semaglutide, it’s paramount that you exercise caution and moderation.

Understanding the potential risks and how alcohol interacts with semaglutide is crucial to protecting your health and ensuring the effectiveness of your treatment. Be sure to speak to your doctor before drinking on semaglutide.

If you’re seeking to lose weight, the Sanctuary Wellness Institute’s medical weight loss program could be the solution you’ve been looking for. We can connect you with a weight loss doctor who can evaluate you for semaglutide treatment. If they deem you eligible for it, you can get your medication delivered straight to your home. Best of all, when you partner with the Sanctuary you can attend your initial consultation and all follow-up appointments online.

Book a complimentary evaluation today to discover whether you’re eligible for semaglutide for weight loss.

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